Description
Product Characteristics:
Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development.
Subcellular location: Secreted
Synonyms: CLF, NR6, CISS, CISS1, CLF-1, zcytor5, Cytokine receptor-like factor 1, Cytokine-like factor 1, CRLF1, UNQ288/PRO327
Target Information: This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009]